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Anti -MyD88 Rabbit pAb

貨號:GB111554

品牌:Servicebio

價格:¥650

規格: 100 μl

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Product Information

 

Description MyD88 rabbit polyclonal
Protein full name Myeloid differentiation primary response protein MyD88
Synonyms MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88)
Immunogen KLH conjugated Synthetic peptide
corresponding to Human MyD88
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus, Cytoplasm
Uniprot ID Q99836, P22366, Q6Y1S1

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1: 1200-1: 2400 small intestine, lung, pneumonia

 


 

Background
 

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.

 


 

Images

 


Immunohistochemistry analysis of paraffin-embedded human small intestine using MyD88 (GB111554) at dilution of 1: 1200
 

Immunohistochemistry analysis of paraffin-embedded mouse lung using MyD88 (GB111554) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat pneumonia using MyD88 (GB111554) at dilution of 1: 1200

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
 

 

NOTE: This product is intended for research only.

 

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