|Description||MyD88 rabbit polyclonal|
|Protein full name||Myeloid differentiation primary response protein MyD88|
|Synonyms||MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88)|
|Immunogen||KLH conjugated Synthetic peptide
corresponding to Human MyD88
|Subcellular location||Nucleus, Cytoplasm|
|Uniprot ID||Q99836, P22366, Q6Y1S1|
|IHC||Human, Mouse, Rat||1: 1200-1: 2400||small intestine, lung, pneumonia|
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.
Immunohistochemistry analysis of paraffin-embedded human small intestine using MyD88 (GB111554) at dilution of 1: 1200
Immunohistochemistry analysis of paraffin-embedded mouse lung using MyD88 (GB111554) at dilution of 1: 1200
Immunohistochemistry analysis of paraffin-embedded rat pneumonia using MyD88 (GB111554) at dilution of 1: 1200
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.|
|Storage Buffer||PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.