|Description||PSD93 rabbit polyclonal|
|Protein full name||Disks large homolog 2|
|Synonyms||Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93, DLG2, channel-associated protein of synapses, Chapsyn-1, discs large 2, discs large homolog 2, discs, Post Synaptic Density 93, Postsynaptic density protein PSD-93, protein phosphatase 1, regulatory subunit 58, Dlgh2, PPP1R58, Gm1197|
|Immunogen||Recombinant protein corresponding to
|Predicted MW.||98 kDa|
|Observed MW.||110 kDa|
|WB||Human||1: 500-1: 1000||Hela, SH-SY5Y, Jurkat|
Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97. It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Western blot analysis of PSD93 (GB111562)
at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: SH-SY5Y cell lysate
Lane 3: Jurkat cell lysate
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.|
|Storage Buffer||PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.